Journal
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Volume 80, Issue -, Pages 13-16Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2017.07.038
Keywords
Redox gradient; Metabolic gradient; Wound healing; Reactive oxygen species; Signaling; Neutrophil; Chemotaxis; NADPH oxidase; Zebrafish; Biosensor; Imaging
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Funding
- NIH [GM099970]
- American Asthma Foundation Scholar grant
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Evidence emerges that redox gradients regulate morphogenesis, inflammation, regeneration, and healing of tissues. At the example of redox signaling during the zebrafish wound response, I briefly discuss current ideas on how such patterns might be sensed and spatially regulated to guide physiological processes over distances in animals. (C) 2017 Elsevier Ltd. All rights reserved.
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