Journal
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Volume 86, Issue -, Pages 44-49Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2018.02.018
Keywords
Monocyte; Dendritic cell; Inflammation; Auto-immune disease; Cancer
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Funding
- program Investissements d'Avenir from Agence Nationale de la Recherche [ANR-10-LABX-0043, ANR-10-IDEX-0001-02 PSL]
- Fondation Bristol-Myers Squibb pour la Recherche en Immuno-Oncologie
- INSERM
- Universite Paris Descartes
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When entering tissues, monocytes can differentiate into cells that share morphological and functional features with either dendritic cells (DC) or macrophages. Monocyte-derived DC have been observed in humans at mucosal tissues and in inflammatory settings, where they are usually referred to as inflammatory DC. In this chapter, we review recent studies on the characterization of these cells in humans. We also discuss nomenclature and examine the criteria defining in vivo-differentiated human mo-DC. (C) 2018 Elsevier Ltd. All rights reserved.
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