Journal
CRITICAL CARE
Volume 16, Issue 4, Pages -Publisher
BMC
DOI: 10.1186/cc11252
Keywords
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Categories
Funding
- National Institutes of Health [T32 AA013528, R21 HL110044, K23AR054334, K24 RR023356, U54 RR-024380, P50 AA-013757]
- Atlanta Clinical and Translational Science Institute [UL1 RR025008]
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The growing basic and clinical investigations into the extraskeletal effects of vitamin D have revealed roles in the functioning of the immune system, generating interesting questions about this nutrient's connections to sepsis. This article briefly reviews the current science of the function of vitamin D in the immune system as well as the emerging clinical literature regarding its associations with respiratory infections, sepsis, and critical illness. Finally, we offer views on the potential future directions for research in the field by outlining potential relevant scenarios and outcomes.
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