Journal
SCIENCE CHINA-LIFE SCIENCES
Volume 61, Issue 4, Pages 400-414Publisher
SCIENCE PRESS
DOI: 10.1007/s11427-017-9271-1
Keywords
magnetic nanoparticles; therapeutic delivery; magnetic hyperthermia treatment; theranostics
Categories
Funding
- National Natural Science Foundation of China [81571809, 81771981, 31400663, 21376192]
- Natural Science Foundation of Shaanxi Province [2015JM2063, 2017JM2031]
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Nanotechnology holds a promising potential for developing biomedical nanoplatforms in cancer therapy. The magnetic nanoparticles, which integrate uniquely appealing features of magnetic manipulation, nanoscale heat generator, localized magnetic field and enzyme-mimics, prompt the development and application of magnetic nanoparticles-based cancer medicine. Considerable success has been achieved in improving the magnetic resonance imaging (MRI) sensitivity, and the therapeutic function of the magnetic nanoparticles should be given adequate attention. This work reviews the current status and applications of magnetic nanoparticles based cancer therapy. The advantages of magnetic nanoparticles that may contribute to improved therapeutics efficacy of clinic cancer treatment are highlighted here.
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