Related references
Note: Only part of the references are listed.Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B
Alisa F. Zyryanova et al.
SCIENCE (2018)
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
Shawn Q. Zheng et al.
NATURE METHODS (2017)
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
Ali Punjani et al.
NATURE METHODS (2017)
Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury
Austin Chou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Endoplasmic reticulum proteostasis in glioblastoma-From molecular mechanisms to therapeutic perspectives
Joanna Obacz et al.
SCIENCE SIGNALING (2017)
Endoplasmic reticulum proteostasis in glioblastoma-From molecular mechanisms to therapeutic perspectives
Joanna Obacz et al.
SCIENCE SIGNALING (2017)
The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic Significance
Paolo Remondelli et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Endoplasmic reticulum proteostasis impairment in aging
Gabriela Martinez et al.
AGING CELL (2017)
Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response
Brian R. Hearn et al.
CHEMMEDCHEM (2016)
Gctf: Real-time CTF determination and correction
Kai Zhang
JOURNAL OF STRUCTURAL BIOLOGY (2016)
Crystal structure of eukaryotic translation initiation factor 2B
Kazuhiro Kashiwagi et al.
NATURE (2016)
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
Dari Kimanius et al.
ELIFE (2016)
The Phyre2 web portal for protein modeling, prediction and analysis
Lawrence A. Kelley et al.
NATURE PROTOCOLS (2015)
Architecture of the eIF2B regulatory subcomplex and its implications for the regulation of guanine nucleotide exchange on eIF2
Bernhard Kuhle et al.
NUCLEIC ACIDS RESEARCH (2015)
Mutations in a translation initiation factor identify the target of a memory-enhancing compound
Yusuke Sekine et al.
SCIENCE (2015)
Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity
M. Halliday et al.
CELL DEATH & DISEASE (2015)
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response
Carmela Sidrauski et al.
ELIFE (2015)
The small molecule ISRIB reverses the effects of elF2α phosphorylation on translation and stress granule assembly
Carmela Sidrauski et al.
ELIFE (2015)
The Scanning Mechanism of Eukaryotic Translation Initiation
Alan G. Hinnebusch
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
Insights into the Architecture of the elF2Bα/β/δ Regulatory Subcomplex
Andrew M. Bogorad et al.
BIOCHEMISTRY (2014)
Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation
Noel C. Wortham et al.
FASEB JOURNAL (2014)
Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α
Gonzalo Viana Di Prisco et al.
NATURE NEUROSCIENCE (2014)
eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core
Yuliya Gordiyenko et al.
NATURE COMMUNICATIONS (2014)
Co-Opting the Unfolded Protein Response to Elicit Olfactory Receptor Feedback
Ryan P. Dalton et al.
CELL (2013)
A Yeast Purification System for Human Translation Initiation Factors eIF2 and eIF2Bε and Their Use in the Diagnosis of CACH/VWM Disease
Rogerio A. de Almeida et al.
PLOS ONE (2013)
Pharmacological brake-release of mRNA translation enhances cognitive memory
Carmela Sidrauski et al.
ELIFE (2013)
The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges
Alan G. Hinnebusch et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
electronic Ligand Builder and Optimization Workbench (eLBOW): a tool for ligand coordinate and restraint generation
Nigel W. Moriarty et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2009)
Crystal Structure of the α Subunit of Human Translation Initiation Factor 2B
Takuya B. Hiyama et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Translational control of hippocampal synaptic plasticity and memory by the eIF2α kinase GCN2
M Costa-Mattioli et al.
NATURE (2005)
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
DH Munn et al.
IMMUNITY (2005)
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
KM Vattem et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation
E Gomez et al.
EMBO JOURNAL (2002)
Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter
PAJ Leegwater et al.
NATURE GENETICS (2001)
Tight binding of the phosphorylated α subunit of initiation factor 2 (eIF2α) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation
T Krishnamoorthy et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein
DD Williams et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulated translation initiation controls stress-induced gene expression in mammalian cells
HP Harding et al.
MOLECULAR CELL (2000)
Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling
P Schuck
BIOPHYSICAL JOURNAL (2000)
Share Paper
