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The Role of Ca2+-ATPase 2a (ATP2A2), Ryanodine Receptors (RYR2), and Calsequestrin (CASQ2) Gene Polymorphisms in the Development of Heart Failure

Journal

RUSSIAN JOURNAL OF GENETICS
Volume 54, Issue 6, Pages 604-608

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S102279541806008X

Keywords

heart failure; contractile dysfunction; ATP2A2; RYR2; CASQ2

Funding

  1. Russian Foundation for Basic Research [17-04-01450 A]

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This review contains data reflecting the role of polymorphisms and mutations of the genes of proteins Ca2+-ATPase 2a, ryanodine receptors, and calsequestrin of the Ca2+-transporting system of the sarcoplasmic reticulum of cardiomyocytes in the formation of contractile myocardial dysfunction.

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