Journal
RHEUMATOLOGY
Volume 57, Issue -, Pages 3-9Publisher
OXFORD UNIV PRESS
DOI: 10.1093/rheumatology/key014
Keywords
prevention; osteoarthritis; risk factors; incidence; progression
Categories
Funding
- Dutch Arthritis Foundation (Dutch Arthritis Foundation)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) [AR068493 (R21)]
Ask authors/readers for more resources
This narrative review discusses the potential of prevention of OA in different stages of the disease. The theoretical background for primary prevention (i.e. prevention of occurrence of definite structural or clinical OA in subjects free of the disease) and secondary prevention (i.e. prevention of progression of the disease in subjects with pre-clinical pathological changes to the joint) is provided and evidence for effective strategies is discussed. Since direct evidence for the prevention of OA development and progression is scarce, indirect evidence enhancing our current knowledge on the potential of OA prevention is additionally discussed. Also, implications of preventive strategies for study design and public health are considered. Prevention of OA has great potential, but as deliberated in the current review, there are still large gaps in our current knowledge and the implications of preventive strategies for the development and progression of OA require consideration.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available