Journal
IEEE JOURNAL OF SOLID-STATE CIRCUITS
Volume 50, Issue 1, Pages 375-390Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/JSSC.2014.2364036
Keywords
Analog front-end (AFE); asynchronous logic; capacitive feedback chopper stabilized instrumental amplifier (CCIA); electrocardiography (ECG); fast Fourier transform (FFT); implantable system; kickback noise; minimum energy point (MEP); mm(3)
Categories
Funding
- National Heart, Lung, and Blood Institute [R01-HL118304]
- Leducq Foundation
- University of Michigan
- National Science Foundation, DARPA/StartNet Terraswarm Research Center
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A syringe-implantable electrocardiography (ECG) monitoring system is proposed. The noise optimization and circuit techniques in the analog front-end (AFE) enable 31 nA current consumption while a minimum energy computation approach in the digital back-end reduces digital energy consumption by 40%. The proposed SoC is fabricated in 65 nm CMOS and consumes 64 nW while successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.
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