4.3 Article

RND transporters in the living world

Journal

RESEARCH IN MICROBIOLOGY
Volume 169, Issue 7-8, Pages 363-371

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.resmic.2018.03.001

Keywords

Superfamily; Phylogeny; Quaternary structure

Categories

Funding

  1. National Institutes of Health [R01 AI-9644]

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Transporters of the RND superfamily are well-known as the major drug efflux pumps of Gram-negative bacteria. However, they are widespread in organisms ranging from Archaea to Eukaryotes, and perform diverse functions. This review gives a brief overview of these diverse members of the superfamily with emphasis on their structure and functions. (C) 2018 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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