Nanomaterials for hard-soft tissue interfaces

The field of interfacial tissue engineering is striving to restore the structural and functional characteristics of hard-soft tissue interfaces, which include osteochondral and bone-tendon/ligament interfaces. This chapter first discusses the structural and functional characteristics of these interfaces and then describes the two main types of nanomaterials emerging in interfacial tissue engineering strategies: nanoparticles and nanofibers. Additionally, the chapter discusses approaches used to employ these nanomaterials in interfacial constructs.