Journal
AIDS AND BEHAVIOR
Volume 17, Issue 1, Pages 74-85Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10461-012-0308-9
Keywords
Infectious disease; Self-awareness; Mnemonic devices; Medications
Funding
- NIDA NIH HHS [DA031098, T32 DA031098] Funding Source: Medline
- NIMH NIH HHS [P30 MH062512, R01 MH073419, MH62512, R03 MH078785, MH073419, MH078785] Funding Source: Medline
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Forgetting is the most commonly endorsed reason for missing an antiretroviral therapy (ART) dose, yet little is known about the prevalence, predictors, and effectiveness of the mnemonic strategies to support ART adherence. The current study assessed 28 self-reported memory-based medication strategies in 233 HIV-infected individuals with 30-day ART adherence measured via the medication event monitoring system. Participants endorsed using multiple (8.7 +/- A 5.6) strategies with the most common being internally-driven. More frequent strategy use was uniquely associated with affective distress, dependent daily functioning, higher non-ART pill burden, and poorer ART adherence. Individuals who used strategies frequently, but perceived them as minimally effective, had more affective, physical, and functional distress. More frequent strategy use was associated with worse ART adherence and was unrelated to perceived effectiveness. Primary reliance on internally-based mnemonic strategies may reflect a lack of awareness of adherence behaviors and may be insufficient to support optimal ART adherence in vulnerable populations.
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