Journal
PSYCHOLOGICAL MEDICINE
Volume 49, Issue 5, Pages 861-867Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0033291718001563
Keywords
Complicated grief; persistent complex bereavement disorder; prolonged grief disorder; prolonged grief
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Funding
- National Institute of Health [R01MH070741, R01MH060783, R01MH085297, R01MH085288, R01MH085308]
- American Foundation for Suicide Prevention [LSRG-S-172-12]
- Congressionally Directed Medical Research Program [W81XWH-15-2-0042, W81XWH-15-2-0043]
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Background The World Health Organization (WHO) International Classification of Disease (ICD-11) is expected to include a new diagnosis for prolonged grief disorder (ICD-11(PGD)). This study examines the validity and clinical utility of the ICD-11(PGD) guideline by testing its performance in a well-characterized clinical sample and contrasting it with a very different criteria set with the same name (PGD(PLOS)). Methods We examined data from 261 treatment-seeking participants in the National Institute of Mental Health (NIMH)-sponsored multicenter clinical trial to determine the rates of diagnosis using the ICD-11(PGD) guideline and compared these with diagnosis using PGD(PLOS) criteria. Results The ICD-11(PGD) guideline identified 95.8% [95% confidence interval (CI) 93.3-98.2%] of a treatment-responsive cohort of patients with distressing and impairing grief. PGD(PLOS) criteria identified only 59.0% (95% CI 53.0-65.0%) and were more likely to omit those who lost someone other than a spouse, were currently married, bereaved by violent means, or not diagnosed with co-occurring depression. Those not diagnosed by PGD(PLOS) criteria showed the same rate of treatment response as those who were diagnosed. Conclusions The ICD-11(PGD) diagnostic guideline showed good performance characteristics in this sample, while PGD(PLOS) criteria did not. Limitations of the research sample used to derive PGD(PLOS) criteria may partly explain their poor performance in a more diverse clinical sample. Clinicians and researchers need to be aware of the important difference between these two identically named diagnostic methods.
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