4.7 Article

Macrolide- and Rifampin-Resistant Rhodococcus equi on a Horse Breeding Farm, Kentucky, USA

Journal

EMERGING INFECTIOUS DISEASES
Volume 19, Issue 2, Pages 282-285

Publisher

CENTERS DISEASE CONTROL
DOI: 10.3201/eid1902.121210

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Funding

  1. Hodgson Equine Research Endowment of the University of Georgia
  2. Link Equine Research Endowment of Texas AM University
  3. Grayson-Jockey Club Research Foundation

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Macrolide and rifampin resistance developed on a horse breeding farm after widespread use was instituted for treatment of subclinical pulmonary lesions in foals. Resistance occurred in 6(24%) of 25 pretreatment and 8(62%) of 13 (62%) posttreatment isolates from affected foals. Drug-resistant isolates formed 2 distinct genotypic clusters.

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