Related references
Note: Only part of the references are listed.Neurotrophin signalling: novel insights into mechanisms and pathophysiology
Mariela Mitre et al.
CLINICAL SCIENCE (2017)
More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy
Shang-Der Chen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons
Stefanie Traub et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)
Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?
Raymond T. Bartus et al.
NEUROBIOLOGY OF DISEASE (2017)
Multiplex quantitative assays indicate a need for re-evaluating reported small-molecule TrkB agonists
Umed Boltaev et al.
SCIENCE SIGNALING (2017)
Multiplex quantitative assays indicate a need for re-evaluating reported small-molecule TrkB agonists
Umed Boltaev et al.
SCIENCE SIGNALING (2017)
Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons
Vsevolod Telezhkin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)
Activin A directs striatal projection neuron differentiation of human pluripotent stem cells
Charles Arber et al.
DEVELOPMENT (2015)
Gadd45b is a Novel Mediator of Neuronal Apoptosis in Ischemic Stroke
Bin Liu et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2015)
Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects
Hongkai Zhang et al.
NATURE COMMUNICATIONS (2015)
Optimizing the use of anti-tumor necrosis factor in the management of patients with Crohn's disease
Douglas L. Nguyen et al.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2015)
Withdrawal of BDNF from Hippocampal Cultures Leads to Changes in Genes Involved in Synaptic Function
Abigail Mariga et al.
DEVELOPMENTAL NEUROBIOLOGY (2015)
A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington's Disease
Daniel Todd et al.
PLOS ONE (2014)
Selecting Agonists from Single Cells Infected with Combinatorial Antibody Libraries
Hongkai Zhang et al.
CHEMISTRY & BIOLOGY (2013)
A Small Molecule TrkB Ligand Reduces Motor Impairment and Neuropathology in R6/2 and BACHD Mouse Models of Huntington's Disease
Danielle A. Simmons et al.
JOURNAL OF NEUROSCIENCE (2013)
Activation of TrkB with TAM-163 Results in Opposite Effects on Body Weight in Rodents and Non-Human Primates
Mylene Perreault et al.
PLOS ONE (2013)
Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells
Jia Xie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A TrkB Small Molecule Partial Agonist Rescues TrkB Phosphorylation Deficits and Improves Respiratory Function in a Mouse Model of Rett Syndrome
Danielle A. Schmid et al.
JOURNAL OF NEUROSCIENCE (2012)
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome
Ruben Deogracias et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Activin induces cortical interneuron identity and differentiation in embryonic stem cell-derived telencephalic neural precursors
Serafi Cambray et al.
NATURE COMMUNICATIONS (2012)
Pharmacological characterization of six trkB antibodies reveals a novel class of functional agents for the study of the BDNF receptor
M. Cazorla et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Potential therapeutic uses of BDNF in neurological and psychiatric disorders
Alan H. Nagahara et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons
Yuanyuan Ji et al.
NATURE NEUROSCIENCE (2010)
NEURONS ASSOCIATED WITH AGGRECAN-BASED PERINEURONAL NETS ARE PROTECTED AGAINST TAU PATHOLOGY IN SUBCORTICAL REGIONS IN ALZHEIMER'S DISEASE
M. Morawski et al.
NEUROSCIENCE (2010)
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
Sung-Wuk Jang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
An Agonistic TrkB mAb Causes Sustained TrkB Activation, Delays RGC Death, and Protects the Retinal Structure in Optic Nerve Axotomy and in Glaucoma
Yujing Bai et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
Heterozygous NTF4 Mutations Impairing Neurotrophin-4 Signaling in Patients with Primary Open-Angle Glaucoma
Francesca Pasutto et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2009)
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Stuart M. Chambers et al.
NATURE BIOTECHNOLOGY (2009)
Short-Term Striatal Gene Expression Responses to Brain-Derived Neurotrophic Factor Are Dependent on MEK and ERK Activation
Ozgun Gokce et al.
PLOS ONE (2009)
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice
Danielle A. Simmons et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis
Dengke K. Ma et al.
SCIENCE (2009)
TrkB agonists ameliorate obesity and associated metabolic conditions in mice
David Tsao et al.
ENDOCRINOLOGY (2008)
Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21waf1/cip1 in cell cycle-independent neuroprotection
Brett Langley et al.
JOURNAL OF NEUROSCIENCE (2008)
Up-Regulation of Brain-Derived Neurotrophic Factor by Application of Fibroblast Growth Factor-2 to the Cut Optic Nerve Is Important for Long-Term Survival of Retinal Ganglion Cells
Rosa E. Blanco et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21Waf1/Cip1 as a novel mechanism of neuroprotection by glucocorticoids
Christoph Harms et al.
JOURNAL OF NEUROSCIENCE (2007)
FDA drug approval summary: Panitumumab (Vectibix (TM))
Ruthann M. Giusti et al.
ONCOLOGIST (2007)
Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses
Zhiping P. Pang et al.
JOURNAL OF NEUROSCIENCE (2006)
Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type A GABA receptor α4 subunits in hippocampal neurons
Daniel S. Roberts et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities
Ming D. Qian et al.
JOURNAL OF NEUROSCIENCE (2006)
The neuroplasticity-associated Arc gene is a direct transcriptional target of early growth response (Egr) transcription factors
L Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
N Ferrara et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Mutation screen of the brain derived neurotrophic factor gene (BDNF):: Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder
S Friedel et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2005)
Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death
K Imaizumi et al.
JOURNAL OF NEUROSCIENCE (2004)
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
GSH Yeo et al.
NATURE NEUROSCIENCE (2004)
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
MF Egan et al.
CELL (2003)
The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes
Y Yin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The non-peptidyl fungal metabolite L-783,281 activates TRK neurotrophin receptors
N Wilkie et al.
JOURNAL OF NEUROCHEMISTRY (2001)
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis
G Ochs et al.
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS (2000)
Neurotrophin signal transduction in the nervous system
DR Kaplan et al.
CURRENT OPINION IN NEUROBIOLOGY (2000)