4.5 Review

Polyurethanes in cardiovascular prosthetics

Journal

POLYMER BULLETIN
Volume 75, Issue 9, Pages 4311-4325

Publisher

SPRINGER
DOI: 10.1007/s00289-017-2266-x

Keywords

Polyurethanes; Tissue-engineered vascular grafts; Electrospinning; Electrospray; Biocompatibility; Biostability

Funding

  1. Russian Science Foundation [17-75-30009]
  2. Russian Science Foundation [17-75-30009] Funding Source: Russian Science Foundation

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Polyurethane has become a popular material in biomedical industry because of its good mechanical properties as well as biocompatibility and hemocompatibility. However, the material degrades during a long-term functioning of polyurethane grafts. To increase biostability, novel polyurethanes with a siloxane segment, polycarbonate polyurethanes, and nanocomposite polyurethanes are offered. Along with novel polyurethanes, modern tissue engineering technologies are well applicable for manufacture of the polyurethane products with unique properties. Different polyurethanes and modern technologies for producing cardiovascular grafts of polyurethane are discussed.

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