Journal
PLANT SCIENCE
Volume 274, Issue -, Pages 485-491Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.plantsci.2018.06.026
Keywords
ATG proteins; De novo peroxisome biogenesis; Peroxins; Pexophagy; Pexophagy receptor; Selective autophagy
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Funding
- Research Grants Council of Hong Kong [G-CUHK402/15, G-CUHK403/17, CUHK14130716, CUHK14102417, C4011-14R, C4012-16E, C4002-17G, AoE/M-05/12]
- National Natural Science Foundation of China [31470294, 31670179]
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Peroxisome, a single-membrane organelle conserved in eukaryotic, is responsible for a series of oxidative reactions with its specific enzymatic components. A counterbalance between peroxisome biogenesis and degradation is crucial for the homeostasis of peroxisomes. One such degradation mechanism, termed pexophagy, is a type of selective autophagic process to deliver the excess/damaged peroxisomes into the vacuole. In plants, pexophagy is involved in the remodeling of seedlings and quality control of peroxisomes. Here, we describe the recent advance in plant pexophagy, with a focus to discuss the key regulators in plants in comparison with those in yeast and mammals, as well as future directions for pexophagy studies in plants.
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