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Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet
Shireesh Srivastava et al.
FASEB JOURNAL (2012)
Intrahepatic Diacylglycerol Content Is Associated With Hepatic Insulin Resistance in Obese Subjects
Faidon Magkos et al.
GASTROENTEROLOGY (2012)
Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome
Anne Vrieze et al.
GASTROENTEROLOGY (2012)
Acute Free Fatty Acid Elevation Eliminates Endurance Training Effect on Insulin Sensitivity
Lisa S. Chow et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Long- and Medium-Chain Fatty Acids Induce Insulin Resistance to a Similar Extent in Humans Despite Marked Differences in Muscle Fat Accumulation
Joris Hoeks et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Metabolomic Profiling of Amino Acids and β-Cell Function Relative to Insulin Sensitivity in Youth
Sara F. Michaliszyn et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Metabolomics reveals increased isoleukotoxin diol (12,13-DHOME) in human plasma after acute Intralipid infusion
Lindsay M. Edwards et al.
JOURNAL OF LIPID RESEARCH (2012)
Novel biomarkers for pre-diabetes identified by metabolomics
Rui Wang-Sattler et al.
MOLECULAR SYSTEMS BIOLOGY (2012)
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
Atsuhiko Ichimura et al.
NATURE (2012)
The role of mitochondria in insulin resistance and type 2 diabetes mellitus
Julia Szendroedi et al.
NATURE REVIEWS ENDOCRINOLOGY (2012)
The role of the gut microbiota in nutrition and health
Harry J. Flint et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2012)
Palmitoleate Induces Hepatic Steatosis but Suppresses Liver Inflammatory Response in Mice
Xin Guo et al.
PLOS ONE (2012)
Adipose tissue palmitoleic acid and obesity in humans: does it behave as a lipokine?
Jian Gong et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
Effects of supplemented isoenergetic diets differing in cereal fiber and protein content on insulin sensitivity in overweight humans
Martin O. Weickert et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction
Jeffrey D. Browning et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
Central infusion of ketone bodies modulates body weight and hepatic insulin sensitivity by modifying hypothalamic leptin and insulin signaling pathways in type 2 diabetic rats
Sunmin Park et al.
BRAIN RESEARCH (2011)
Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease
Nishanth E. Sunny et al.
CELL METABOLISM (2011)
Amino Acid-Dependent Activation of Liver Estrogen Receptor Alpha Integrates Metabolic and Reproductive Functions via IGF-1
Sara Della Torre et al.
CELL METABOLISM (2011)
Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates
Ee L. Lim et al.
CLINICAL SCIENCE (2011)
Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling
Louise D. Hoeg et al.
DIABETES (2011)
Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways
Fei Xiao et al.
DIABETES (2011)
Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance Another Paradox in Endurance-Trained Athletes?
Francesca Amati et al.
DIABETES (2011)
Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine
Rajagopal V. Sekhar et al.
DIABETES CARE (2011)
Liver ATP Synthesis Is Lower and Relates to Insulin Sensitivity in Patients With Type 2 Diabetes
Albrecht Ingo Schmid et al.
DIABETES CARE (2011)
Hyperaminoacidaemia at postprandial levels does not modulate glucose metabolism in type 2 diabetes mellitus
M. Bassil et al.
DIABETOLOGIA (2011)
Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men
Lindsay M. Edwards et al.
FASEB JOURNAL (2011)
Malnutrition Impairs Interferon Signaling Through mTOR and FoxO Pathways in Patients With Chronic Hepatitis C
Masao Honda et al.
GASTROENTEROLOGY (2011)
A High-Fat Diet Elicits Differential Responses in Genes Coordinating Oxidative Metabolism in Skeletal Muscle of Lean and Obese Individuals
K. E. Boyle et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Dietary Methionine Restriction Increases Fat Oxidation in Obese Adults with Metabolic Syndrome
Eric P. Plaisance et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Three Weeks on a High-Fat Diet Increases Intrahepatic Lipid Accumulation and Decreases Metabolic Flexibility in Healthy Overweight Men
Noud A. van Herpen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans
Eugene P. Rhee et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Insulin sensitivity is not associated with palmitoleate availability in obese humans
Elisa Fabbrini et al.
JOURNAL OF LIPID RESEARCH (2011)
Metabolite profiles and the risk of developing diabetes
Thomas J. Wang et al.
NATURE MEDICINE (2011)
Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men
Myrte Brands et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2011)
Is Intestinal Gluconeogenesis a Key Factor in the Early Changes in Glucose Homeostasis Following Gastric Bypass?
Mark Thomas Hayes et al.
OBESITY SURGERY (2011)
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
Naoki Kumashiro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Acute elevation of plasma lipids does not affect ATP synthesis in human skeletal muscle
A. Brehm et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
β-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle
Takashi Yamada et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain
Francois R. Jornayvaz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine
Elango Kathirvel et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease
Zhigang Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
Sa'ad H. Al-Lahham et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Mitochondrial dysfunction and lipotoxicity
Patrick Schrauwen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Glycine regulates inflammatory markers modifying the energetic balance through PPAR and UCP-2
J. C. Almanza-Perez et al.
BIOMEDICINE & PHARMACOTHERAPY (2010)
Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-α
Kristin R. Freeland et al.
BRITISH JOURNAL OF NUTRITION (2010)
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
Da Young Oh et al.
CELL (2010)
Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue
Ying Cheng et al.
DIABETES (2010)
Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle
Natalie Lefort et al.
DIABETES (2010)
Circulating Palmitoleate Strongly and Independently Predicts Insulin Sensitivity in Humans
Norbert Stefan et al.
DIABETES CARE (2010)
Adipose tissue fatty acids and insulin sensitivity in elderly men
D. Iggman et al.
DIABETOLOGIA (2010)
Regulation of adipokine production in human adipose tissue by propionic acid
Sa'ad H. Al-Lahham et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2010)
Dietary Fiber Supplements: Effects in Obesity and Metabolic Syndrome and Relationship to Gastrointestinal Functions
Athanasios Papathanasopoulos et al.
GASTROENTEROLOGY (2010)
Activation of N-Methyl-D-aspartate (NMDA) Receptors in the Dorsal Vagal Complex Lowers Glucose Production
Carol K. L. Lam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
α-Oxocarboxylic Acids
Robert C. Kerber et al.
JOURNAL OF CHEMICAL EDUCATION (2010)
The Effect of Branched Chain Amino Acids on Skeletal Muscle Mitochondrial Function in Young and Elderly Adults
Laura L. Tatpati et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Effect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals
Alberto O. Chavez et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Lipid-induced insulin resistance: unravelling the mechanism
Varman T. Samuel et al.
LANCET (2010)
Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome
Guo-Xin Hu et al.
MEDICAL HYPOTHESES (2010)
Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity
Stephanie J. Mihalik et al.
OBESITY (2010)
Microbiota and SCFA in Lean and Overweight Healthy Subjects
Andreas Schwiertz et al.
OBESITY (2010)
α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population
Walter E. Gall et al.
PLOS ONE (2010)
Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting
Karsten Suhre et al.
PLOS ONE (2010)
Fed-state clamp stimulates cellular mechanisms of muscle protein anabolism and modulates glucose disposal in normal men
Olasunkanmi A. J. Adegoke et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Inhibiting gluconeogenesis prevents fatty acid-induced increases in endogenous glucose production
Sylvia Kehlenbrink et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Expression of short-chain fatty acid receptor GPR41 in the human colon
Hideaki Tazoe et al.
BIOMEDICAL RESEARCH-TOKYO (2009)
GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon
Muthusamy Thangaraju et al.
CANCER RESEARCH (2009)
A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
Christopher B. Newgard et al.
CELL METABOLISM (2009)
Muscle acylcarnitines during short-term fasting in lean healthy men
Maarten R. Soeters et al.
CLINICAL SCIENCE (2009)
Ectopic lipids and organ function
Julia Szendroedi et al.
CURRENT OPINION IN LIPIDOLOGY (2009)
Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance
Jacob M. Haus et al.
DIABETES (2009)
Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
Zhanguo Gao et al.
DIABETES (2009)
Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women
Kim M. Huffman et al.
DIABETES CARE (2009)
Betaine for Nonalcoholic Fatty Liver Disease: Results of a Randomized Placebo-Controlled Trial
Manal F. Abdelmalek et al.
HEPATOLOGY (2009)
Abnormal Hepatic Energy Homeostasis in Type 2 Diabetes
Julia Szendroedi et al.
HEPATOLOGY (2009)
Changes in Basal and Insulin and Amino Acid Response of Whole Body and Skeletal Muscle Proteins in Obese Men
Christelle Guillet et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Plasma Acylcarnitine Profiles Suggest Incomplete Long-Chain Fatty Acid β-Oxidation and Altered Tricarboxylic Acid Cycle Activity in Type 2 Diabetic African-American Women
Sean H. Adams et al.
JOURNAL OF NUTRITION (2009)
Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men
Charlotte Brons et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Molecular mechanisms of mTOR-mediated translational control
Xiaoju Max Ma et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors
Kashan Ahmed et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
SIRT1 Knockout Leads to Angiogenesis Deficiency in Adipose Tissue through Macrophage Dysfunction
Fen Xu et al.
DIABETES (2009)
Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study
Paraskevi Detopoulou et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
Haiming Cao et al.
CELL (2008)
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
Timothy R. Koves et al.
CELL METABOLISM (2008)
Glycine regulates the production of pro-inflammatory cytokines in lean and monosodium glutamate-obese mice
F. J. Alarcon-Aguilar et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Glycine treatment decreases proinflammatory cytokines and increases interferon-γ in patients with Type 2 diabetes
M. Cruz et al.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2008)
Effects of dietary fibers on disturbances clustered in the metabolic syndrome
Milagros Galisteo et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2008)
Expression of the short-chain fatty acid receptor, GPR43, in the human colon
Shin-Ichiro Karaki et al.
JOURNAL OF MOLECULAR HISTOLOGY (2008)
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
Thomas Gerken et al.
SCIENCE (2007)
Elevated free fatty acids attenuate the insulin-induced suppression of PDK4 gene expression in human skeletal muscle: Potential role of intramuscular long-chain acyl-coenzyme a
Kostas Tsintzas et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis
Zhenyuan Song et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
A lipidomic analysis of nonalcoholic fatty liver disease
Puneet Puri et al.
HEPATOLOGY (2007)
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
Frederic Tremblay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Sodium acetate induces a metabolic alkalosis but not the increase in fatty acid oxidation observed following bicarbonate ingestion in humans
Gordon I. Smith et al.
JOURNAL OF NUTRITION (2007)
The mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man
Michael Krebs et al.
DIABETES (2007)
Improvement of obesity and glucose tolerance by acetate in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats
Hiromi Yamashita et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2007)
Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes
Julia Szendroedi et al.
PLOS MEDICINE (2007)
The regulation of adipogenesis through GPR120
Chizu Gotoh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The role of gut hormones in glucose homeostasis
Daniel J. Drucker
JOURNAL OF CLINICAL INVESTIGATION (2007)
High-fat/low-carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: An important role for skeletal muscle pyruvate dehydrogenase kinase 4
K. Chokkalingam et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Role of dietary proteins and amino acids in the pathogenesis of insulin resistance
Frederic Tremblay et al.
ANNUAL REVIEW OF NUTRITION (2007)
An obesity-associated gut microbiome with increased capacity for energy harvest
Peter J. Turnbaugh et al.
NATURE (2006)
Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice
E. Korsheninnikova et al.
DIABETOLOGIA (2006)
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
Michael T. Lin et al.
NATURE (2006)
Structure-based design of indole propionic acids as novel PPARα/γ co-agonists
Bernd Kuhn et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice
S Sakakibara et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state
LJC van Loon et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2006)
Branched-chain amino acids: Enzyme and substrate regulation
JT Brosnan et al.
JOURNAL OF NUTRITION (2006)
Role of amino acids in insulin signaling in adipocytes and their potential to decrease insulin resistance of adipose tissue
Charlotte Hinault et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2006)
Mechanisms of Disease: hepatic steatosis in type 2 diabetes - pathogenesis and clinical relevance
Michael Roden
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2006)
Iramyocellular lipid content and molecular adaptations in response to a 1-week high-fat diet
VB Schrauwen-Hinderling et al.
OBESITY RESEARCH (2005)
Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43
YH Hong et al.
ENDOCRINOLOGY (2005)
Plasma palmitoleic acid content and obesity in children
T Okada et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2005)
Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability
F Tremblay et al.
DIABETES (2005)
(D)-β-hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G
AKP Taggart et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
LM Sparks et al.
DIABETES (2005)
Co-ingestion of a protein hydrolysate and amino acid mixture with carbohydrate improves plasma glucose disposal in patients with type 2 diabetes
RJF Manders et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2005)
Dose-response effect of elevated plasma free fatty acid on insulin signaling
R Belfort et al.
DIABETES (2005)
Brached-chain amino acid metabolism: Implications for establishing safe intakes'
SM Hutson et al.
JOURNAL OF NUTRITION (2005)
Branched-chain amino acids and brain function
JD Fernstrom
JOURNAL OF NUTRITION (2005)
Effect of high protein vs high carbohydrate intake on insulin sensitivity, body weight, hemoglobin A1c, and blood pressure in patients with type 2 diabetes mellitus
KR Sargrad et al.
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION (2005)
Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle
DK Richardson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes
G Boden et al.
ANNALS OF INTERNAL MEDICINE (2005)
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: Possible involvement in obesity-linked insulin resistance
L Khamzina et al.
ENDOCRINOLOGY (2005)
Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population
LS Szczepaniak et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
A Hirasawa et al.
NATURE MEDICINE (2005)
Unlike insulin, amino acids stimulate p70S6K but not GSK-3 or glycogen synthase in human skeletal muscle
ZQ Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Nutrient-induced insulin resistance in human skeletal muscle
M Krebs et al.
CURRENT MEDICINAL CHEMISTRY (2004)
Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes
H Storgaard et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
KF Petersen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
YM Xiong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes
SR Kashyap et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Effect of a high-protein, low-carbohydrate diet on blood glucose control in people with type 2 diabetes
MC Gannon et al.
DIABETES (2004)
Differential effect of saturated and polyunsaturated fatty acids on hepatic glucose metabolism in humans
JN Clore et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Glycine intake decreases plasma free fatty acids, adipose cell size, and blood pressure in sucrose-fed rats
M El Hafidi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2004)
Pathogenesis of type 2 diabetes mellitus
RA DeFronzo
MEDICAL CLINICS OF NORTH AMERICA (2004)
Metabolic flexibility
L Storlien et al.
PROCEEDINGS OF THE NUTRITION SOCIETY (2004)
Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle
M Straczkowski et al.
DIABETES (2004)
Direct and indirect effects of amino acids on hepatic glucose metabolism in humans
M Krebs et al.
DIABETOLOGIA (2003)
Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts
CS Stump et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
KF Petersen et al.
SCIENCE (2003)
The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
AJ Brown et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
S Tunaru et al.
NATURE MEDICINE (2003)
Effects of free fatty acids on glucose uptake and utilization in healthy women
CJ Homko et al.
DIABETES (2003)
The metabolic response to ingested glycine
MC Gannon et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2002)
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
DE Kelley et al.
DIABETES (2002)
FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis
G Boden et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α
SI Itani et al.
DIABETES (2002)
Effects of free fatty acids and glycerol on splanchnic glucose metabolism and insulin extraction in nondiabetic humans
P Shah et al.
DIABETES (2002)
Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
M Krebs et al.
DIABETES (2002)
Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans
OP Bachmann et al.
DIABETES (2001)
Lack of hepatic interregulation during inhibition of glycogenolysis in a canine model
K Fosgerau et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2001)
Non-invasive studies of glycogen metabolism in human skeletal muscle using nuclear magnetic resonance spectroscopy
M Roden
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2001)
Acetic acid feeding enhances glycogen repletion in liver and skeletal muscle of rats
T Fushimi et al.
JOURNAL OF NUTRITION (2001)
Effects of insulin and amino acids on leucine metabolism in young and middle-aged humans
L Luzi et al.
EUROPEAN JOURNAL OF NUTRITION (2001)
Effect of glycine on insulin secretion and action in healthy first-degree relatives of type 2 diabetes mellitus patients
M González-Ortiz et al.
HORMONE AND METABOLIC RESEARCH (2001)
Effects of free fatty acids on gluconeogenesis and autoregulation of glucose production in type 2 diabetes
G Boden et al.
DIABETES (2001)
Role of leucine in the regulation of mTOR by amino acids: Revelations from structure-activity studies
CJ Lynch
JOURNAL OF NUTRITION (2001)
Lipid-dependent control of hepatic glycogen stores in healthy humans
H Stingl et al.
DIABETOLOGIA (2001)
4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle
OJ Shah et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2000)
Effect of long-term dietary protein intake on glucose metabolism in humans
T Linn et al.
DIABETOLOGIA (2000)
Serum lipid effects of a high-monounsaturated fat diet based on macadamia nuts
JD Curb et al.
ARCHIVES OF INTERNAL MEDICINE (2000)
Effects of free fatty acid elevation on postabsorptive endogenous glucose production and gluconeogenesis in humans
M Roden et al.
DIABETES (2000)
Changes in phosphatidylcholine fatty acid composition are associated with altered skeletal muscle insulin responsiveness in normal man
JN Clore et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2000)
Quantitative analysis of urinary acylglycines for the diagnosis of beta-oxidation defects using GC-NCI-MS
CG Costa et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2000)