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NATURE (2009)
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J. Bradley Zuchero et al.
NATURE CELL BIOLOGY (2009)
Environmental sensing through focal adhesions
Benjamin Geiger et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon
E. S. Clark et al.
ONCOGENE (2009)
A transcription co-factor integrates cell adhesion and motility with the p53 response
Amanda S. Coutts et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A multi-marker assay to distinguish malignant melanomas from benign nevi
Mohammed Kashani-Sabet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex
Michael R. Schmidt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
NMR solution structures of actin depolymerizing factor homology domains
Alexander K. Goroncy et al.
PROTEIN SCIENCE (2009)
N-WASP and Cortactin Are Involved In Invadopodium-Dependent Chemotaxis to EGF In Breast Tumor Cells
Vera DesMarais et al.
CELL MOTILITY AND THE CYTOSKELETON (2009)
Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor status
P. Hofman et al.
BRITISH JOURNAL OF CANCER (2008)
Cortactin expression predicts poor survival in laryngeal carcinoma
J. H. Gibcus et al.
BRITISH JOURNAL OF CANCER (2008)
Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia
Liang Cai et al.
CELL (2008)
Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement
Victoria Sanz-Moreno et al.
CELL (2008)
WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport
Kenneth G. Campellone et al.
CELL (2008)
Association of cortactin, fascin-1 and epidermal growth factor receptor (EGFR) expression in ovarian carcinomas: Correlation with clinicopathological parameters
Chih-Kung Lin et al.
DISEASE MARKERS (2008)
Arp2/3 complex interactions and actin network turnover in lamellipodia
Frank P. L. Lai et al.
EMBO JOURNAL (2008)
The structural basis of actin filament branching by the Arp2/3 complex
Isabelle Rouiller et al.
JOURNAL OF CELL BIOLOGY (2008)
Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction
Shinsuke Nakao et al.
JOURNAL OF CELL BIOLOGY (2008)
Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments
Lawrence L. LeClaire et al.
JOURNAL OF CELL BIOLOGY (2008)
Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers
Hao Yuan Kueh et al.
JOURNAL OF CELL BIOLOGY (2008)
Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation
Inmaculada Ayala et al.
JOURNAL OF CELL SCIENCE (2008)
WAVE1 is associated with invasiveness and growth of prostate cancer cells
Herman S. Fernando et al.
JOURNAL OF UROLOGY (2008)
Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis
Daniel L. Rocca et al.
NATURE CELL BIOLOGY (2008)
An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity
Akira Terashima et al.
NEURON (2008)
N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer
Tracey A. Martin et al.
CLINICAL & EXPERIMENTAL METASTASIS (2008)
Expression of coronin-3 (coronin-1C) in diffuse gliomas is related to malignancy
D. R. Thal et al.
JOURNAL OF PATHOLOGY (2008)
N-WASP plays a critical role in fibroblast adhesion and spreading
Ashish Misra et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Human subtelomeric WASH genes encode a new subclass of the WASP family
Elena V. Linardopoulou et al.
PLOS GENETICS (2007)
Aberrant expression of cortactin in head and neck squamous cell carcinoma cells is associated with enhanced cell proliferation and resistance to the epidermal growth factor receptor inhibitor gefitinib
Paul Timpson et al.
CANCER RESEARCH (2007)
Cofilin recruitment and function during actin-mediated endocytosis dictated by actin nucleotide state
Voytek Okreglak et al.
JOURNAL OF CELL BIOLOGY (2007)
ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 -: Expressing B-cell chronic lymphocytic leukemia
Avadhut D. Joshi et al.
CLINICAL CANCER RESEARCH (2007)
Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex
Bryan Serrels et al.
NATURE CELL BIOLOGY (2007)
HDAC6 modulates cell motility by altering the acetylation level of cortactin
Xiaohong Zhang et al.
MOLECULAR CELL (2007)
Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma
Keiichi Iwaya et al.
CANCER SCIENCE (2007)
Actin-filament stochastic dynamics mediated by ADF/cofilin
Alphee Michelot et al.
CURRENT BIOLOGY (2007)
F-actin binding is essential for coronin 1B function in vivo
Liang Cai et al.
JOURNAL OF CELL SCIENCE (2007)
Regulation of the actin cytoskeleton in cancer cell migration and invasion
Hideki Yamaguchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia
Emily S. Clark et al.
CANCER RESEARCH (2007)
Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors
Weigang Wang et al.
CANCER RESEARCH (2007)
Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge
Liang Cai et al.
CELL (2007)
A novel role of the actin-nucleating Arp2/3 complex in the regulation of RNA polymerase II-dependent transcription
Youngdong Yoo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation
Scott N. Boyle et al.
CURRENT BIOLOGY (2007)
Coexpression of Arp2 and WAVE2 predicts poor outcome in invasive breast carcinoma
Keiichi Iwaya et al.
MODERN PATHOLOGY (2007)
Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion
Daisuke Yamazaki et al.
JOURNAL OF CELL SCIENCE (2007)
Expression of the WASP verprolin-homologues (WAVE members) in human breast cancer
H. S. Fernando et al.
ONCOLOGY (2007)
Exo70 interacts with the Arp2/3 complex and regulates cell migration
Xiaofeng Zuo et al.
NATURE CELL BIOLOGY (2006)
Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1
William M. Brieher et al.
JOURNAL OF CELL BIOLOGY (2006)
Increased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 correlated with poor prognosis of hepatocellular carcinoma
Lian-Yue Yang et al.
CLINICAL CANCER RESEARCH (2006)
Interaction of SPIN90 with syndapin is implicated in clathrin-mediated endocytic pathway in fibroblasts
Sung Hyun Kim et al.
GENES TO CELLS (2006)
Glia maturation factor-γ is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization
Koji Ikeda et al.
CIRCULATION RESEARCH (2006)
Cortactin overexpression regulates actin-related protein 2/3 complex activity, motility, and invasion in carcinomas with chromosome 11q13 amplification
Brian L. Rothsschild et al.
CANCER RESEARCH (2006)
Arp2/3 ATP hydrolysis-catalysed branch dissociation is critical for endocytic force generation
Adam C. Martin et al.
NATURE CELL BIOLOGY (2006)
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners
Xiaoyang Wu et al.
NATURE CELL BIOLOGY (2006)
Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes
Anika Steffen et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung
S Semba et al.
CLINICAL CANCER RESEARCH (2006)
Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: Defining the stages of invadopodia formation and function
VV Artym et al.
CANCER RESEARCH (2006)
Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis
K Tsujita et al.
JOURNAL OF CELL BIOLOGY (2006)
Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins
T Itoh et al.
DEVELOPMENTAL CELL (2005)
Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions
C Egile et al.
PLOS BIOLOGY (2005)
A conserved trimerization motif controls the topology of short coiled coils
RA Kammerer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility
L Cai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cortactin promotes cell motility by enhancing lamellipodial persistence
NS Bryce et al.
CURRENT BIOLOGY (2005)
N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits
S Benesch et al.
JOURNAL OF CELL SCIENCE (2005)
WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase
K Sossey-Alaoui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2
CF Stovold et al.
BMC CELL BIOLOGY (2005)
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin
H Yamaguchi et al.
JOURNAL OF CELL BIOLOGY (2005)
Conformational changes in the Arp2/3 complex leading to actin nucleation
AA Rodal et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Imaging sites of N-WASP activity in lamellipodia and invadopodia of carcinoma cells
M Lorenz et al.
CURRENT BIOLOGY (2004)
Involvement of Arp2/3 complex in the process of colorectal carcinogenesis
T Otsubo et al.
MODERN PATHOLOGY (2004)
Abi1 is essential for the formation and activation of a WAVE2 signalling complex
M Innocenti et al.
NATURE CELL BIOLOGY (2004)
Purification and architecture of the ubiquitous Wave complex
A Gautreau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Focal adhesion kinase regulation of N-WASP subcellular localization and function
XY Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation
A Steffen et al.
EMBO JOURNAL (2004)
Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp2/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts
CJ Merrifield et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2004)
Activation of endogenous Cdc42 visualized in living cells
P Nalbant et al.
SCIENCE (2004)
Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts
S Verma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor
K Kawamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex
HYH Ho et al.
CELL (2004)
Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP
N Martinez-Quiles et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor
ED Goley et al.
MOLECULAR CELL (2004)
RAD21 and KIAA0196 at 8q24 are amplified and overexpressed in prostate cancer
KP Porkka et al.
GENES CHROMOSOMES & CANCER (2004)
PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia
T Oikawa et al.
NATURE CELL BIOLOGY (2004)
Cooperative roles of Fyn and cortactin in cell migration of metastatic murine melanoma
JH Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90
S Suetsugu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration
S Suetsugu et al.
DEVELOPMENTAL CELL (2003)
Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton
JA Head et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
WAVE2 is required for directed cell migration and cardiovascular development
D Yamazaki et al.
NATURE (2003)
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility
C Yan et al.
EMBO JOURNAL (2003)
ATP hydrolysis on actin-related protein 2/3 complex causes debranching of dendritic actin arrays
C Le Clainche et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion
KA DeMali et al.
JOURNAL OF CELL BIOLOGY (2002)
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
S Eden et al.
NATURE (2002)
Interaction of cortactin and N-WASp with Arp2/3 complex
AM Weaver et al.
CURRENT BIOLOGY (2002)
Crystal structure of Arp2/3 complex
RC Robinson et al.
SCIENCE (2001)
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility
SB Snapper et al.
NATURE CELL BIOLOGY (2001)
Structure of Arp2/3 complex in its activated state and in actin filament branch junctions
N Volkmann et al.
SCIENCE (2001)
CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family
HYH Ho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression
CH Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells
S Lommel et al.
EMBO REPORTS (2001)
Hepatocyte Growth Factor/Scatter Factor-induces phosphorylation of cortactin in A431 cells in a Src kinase-independent manner
L Crostella et al.
ONCOGENE (2001)
The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia
T Stradal et al.
CURRENT BIOLOGY (2001)
Scar/WAVE is localised at the tips of protruding lamellipodia in living cells
P Hahne et al.
FEBS LETTERS (2001)
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
AM Weaver et al.
CURRENT BIOLOGY (2001)
Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites - The role of Fyn and FER kinases
A Kapus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex
SA Weed et al.
JOURNAL OF CELL BIOLOGY (2000)
Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins
L Blanchoin et al.
NATURE (2000)
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
AS Kim et al.
NATURE (2000)
Cell spreading and lamellipodial extension rate is regulated by membrane tension
D Raucher et al.
JOURNAL OF CELL BIOLOGY (2000)
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