Journal
HYPERTENSION RESEARCH
Volume 38, Issue 6, Pages 375-379Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/hr.2015.26
Keywords
cardiac remodeling; cardiovascular diseases; long noncoding RNA
Categories
Funding
- National Science Foundation of China [31100834]
- International Cooperation Foundation of Shaanxi Province [2012KW-32-02]
Ask authors/readers for more resources
Long noncoding RNAs (lncRNAs) are defined as noncoding RNAs that are longer than similar to 200 nucleotides and lack proteinencoding capacity. It has been shown that lncRNAs are involved in multiple human diseases by regulating gene expression at various levels. However, studies of lncRNAs in the cardiovascular system are still in their infancy. A growing body of evidence suggests that lncRNAs are also involved in common cardiovascular diseases, including cardiac development, atherosclerosis, myocardial infarction, heart failure, hypertension and aneurysms. In this review, we summarize the current understanding of lncRNAs in common cardiovascular diseases in an effort to better elucidate the molecular mechanism of cardiovascular diseases and provide a basis for exploring new therapeutic targets in those diseases.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available