Journal
PEDIATRIC CLINICS OF NORTH AMERICA
Volume 65, Issue 4, Pages 739-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pcl.2018.04.006
Keywords
Juvenile idiopathic inflammatory myopathy; Juvenile dermatomyositis; Juvenile polymyositis
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The juvenile idiopathic inflammatory myopathies (JIIMs) are a group of rare, chronic, autoimmune illnesses that affect muscle and, to a lesser extent, skin. The presence of new-onset weakness and, in juvenile dermatomyositis, typical rashes should lead to consideration of these diagnoses. Careful evaluation to exclude alternative diagnoses is needed. Investigations include a variety of blood tests, imaging, and possibly muscle biopsy. Validated clinical assessments are available for monitoring. Standard treatment includes corticosteroids and methotrexate and often extends beyond 1 year. Outcomes are generally good, but disease persistence remains problematic. Early involvement of providers with expertise in JIIM is essential.
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