Journal
PARASITE IMMUNOLOGY
Volume 40, Issue 2, Pages -Publisher
WILEY
DOI: 10.1111/pim.12502
Keywords
cerebral malaria; ILC; microbiota and metabolites; neutrophils; NK cells; Plasmodium; platelets
Categories
Ask authors/readers for more resources
Cerebral malaria (CM) is one complication of Plasmodium parasite infection that can lead to strong inflammatory immune responses in the central nervous system (CNS), accompanied by lung inflammation and anaemia. Here, we focus on the role of the innate immune response in experimental cerebral malaria (ECM) caused by blood-stage murine Plasmodium berghei ANKA infection. While T cells are important for ECM pathogenesis, the role of innate lymphoid cells (ILCs) is only emerging. The role of ILCs and non-lymphoid cells, such as neutrophils and platelets, contributing to the host immune response and leading to ECM and human cerebral malaria (HCM) is reviewed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available