Electrophilic Trifluoromethylthiolation/Semipinacol Rearrangement: Preparation of beta-SCF3 Carbonyl Compounds with alpha-Quaternary Carbon Center

A new and modular electrophilic trifluorome-thylthiolation/semipinacol rearrangement of allylic silyl ethers has been developed under mild conditions. This approach allows the formation of a number of beta-SCF3 carbonyl compounds with a cyclic and all-carbon quaternary center framework in moderate to good yields. It should be noted that this achievement is a metal-free process and just requires the use of simple acetyl chloride as an acidic promoter. Additionally, an interesting H-migration in competition with aryl-migration process was revealed.