Preparation of Benzo[c]carbazol-6-amines via Manganese-Catalyzed Enaminylation of 1-(Pyrimidin-2-yI)-1H-indoles with Ketenimines and Subsequent Oxidative Cyclization

Manganese-catalyzed C-2-H enaminylation of 1-(pyrimidin-2-y1)-1H-indoles with ketenimines is reported. The reaction provided 2-enaminylated indole derivatives in moderate to excellent yields with a broad substrate scope. A migration of the directing group pyrimidinyl occurred during this process. The synthesized 2-enaminyl indoles could be conveniently converted into 5-ary1-7H-benzo[c]carbazol-6-amines.