4.8 Article

Chemo- and Regioselective Hydroarylation of Alkenes with Aromatic Amines Catalyzed by [Ph3C][B(C6F5)4]

Journal

ORGANIC LETTERS
Volume 20, Issue 10, Pages 3101-3104

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b01158

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Funding

  1. National Natural Science Foundation of China [21402135, 21674070]
  2. Project of Scientific and Technologic Infrastructure of Suzhou [SZS201708]
  3. PAPD

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A nonmetal catalyst [Ph3C][B(C6F5)(4)] has been developed to catalyze hydroarylation reaction of alkenes with aromatic primary, secondary, and tertiary amines, which generated aniline derivatives in 32-98% yields. This method is applicable to a wide range of substrates, is highly chemo- and regioselective, and provides a simple and efficient approach for aniline derivative preparation.

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