4.8 Article

Nickel(II)-Catalyzed [8+3]-Cycloaddition of 2-Aryl-N-tosylaziridines with Tropone

Journal

ORGANIC LETTERS
Volume 20, Issue 12, Pages 3570-3573

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b01354

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Funding

  1. NSFC [21372256, 21572264]
  2. Program for Changjiang Scholars and the Innovative Research Team Project [IRT1042]

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The Ni-catalyzed [8 + 3]-cycloaddition of tropone with 2-aryl-N-tosylaziridines proceeded smoothly under mild reaction conditions, affording various 4-tosyl-2,3,4,4a-tetrahydrocyclohepta[b]-[1,4]oxazine derivatives in moderate to excellent yields.

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