4.8 Article

Switchable Decarboxylative Heck-Type Reaction and Oxo-alkylation of Styrenes with N-Hydroxyphthalimide Esters under Photocatalysis

Journal

ORGANIC LETTERS
Volume 20, Issue 12, Pages 3496-3499

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b01268

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Funding

  1. National Natural Science Foundation of China [21425207, 21521002, 21672216, 21702208]
  2. Chinese Academy of Sciences

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The switchable visible-light-mediated decarboxylative Heck-type reaction and oxo-alkylation reaction of N-hydroxyphthalimide esters under photocatalysis were developed. Disubstituted or trisubstituted alkenes were obtained in good yield with high E-selectivity in the presence of Bronsted acid as the additive, while ketones resulted in the absence of the acidic additive.

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