4.8 Article

Synthesis of peri-Substituted (Naphthalen-1-yl)phosphine Ligands by Rhodium(I)-Catalyzed Phosphine-Directed C-H Arylation

Journal

ORGANIC LETTERS
Volume 20, Issue 7, Pages 1810-1814

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b00305

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Funding

  1. National Natural Science Foundation of China [21472060, 21772058, 21072071]
  2. 111 Project [B17019]
  3. self-determined research funds of CCNU from the colleges' basic research and operation of MOE [CCNU17QN0021, CCNU17CG0011, CCNU17KYZHSY07]

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A novel protocol for effective rhodium(I)-catalyzed C-H arylation of tertiary phosphines has been devised. It is amenable to a wide range of substrates and gives the products in moderate to high yields. This strategy provides a simple and efficient route to peri-substituted (naphthalen-1-yl)phosphines.

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