Journal
ORGANIC LETTERS
Volume 20, Issue 5, Pages 1465-1468Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b00327
Keywords
-
Categories
Funding
- Natural Science Foundation of China [31570356]
- NSFC-Shandong Joint Fund for Marine Science Research Centers [U1606403]
- Taishan Scholar Project from Shandong Province of China
Ask authors/readers for more resources
Simpterpenoid A (1), an unprecedented meroterpenoid possessing a highly functionalized cyclohexadiene moiety (ring C) featuring gem-propane-1,2-dione and methylformate groups, was characterized from mangrove-derived Penicillium simplicissimum MA-332. Due to the highly oxygenated and functionalized ring C and lack of some key correlations, the unambiguous assignment of the planar structure and steric configuration was solved by X-ray crystallographic analysis. Compound 1 exhibited inhibitory activity against influenza neuraminidase in nanomolar quantities.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available