Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 22, Pages 4151-4158Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob00860d
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Funding
- National Natural Science Foundation of China [21402005, 21572017]
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N-Alkylated 2-pyridone products were obtained in good to excellent yields through a one-pot procedure involving either normal or interrupted Pummerer reactions between triflic anhydride activated sulfoxides and 2-fluoropyridine derivatives, followed by hydrolysis. This is a rare case that uses 2-fluoropyridine as a nucleophile in Pummerer type reactions.
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