Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 24, Pages 4439-4442Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob00899j
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Funding
- Fundamental Research Funds for the Central Universities [lzujbky-2018-136, lzujbky-2017-k25]
- Department of Education of Guangdong Province [2017KSYS010, 2017KTSCX185, 2016KCXTD005]
- NSFC [21772071, 21472077]
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A novel [3 + 2] cycloaddition reaction of azaoxyallyl cations and aromatic ethylenes has been developed to afford multi-substituted pyrrolidinones in moderate to good yields. This method not only further expands the synthetic utility of -halo hydroxamates, but also provides an alternative method for the synthesis of bioactive molecules containing pyrrolidinones.
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