Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 27, Pages 5016-5020Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob01172a
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Funding
- National Natural Science Foundation of China [21502049, 51573040]
- Planned Science and Technology Project of Hunan Province, China [2015WK3003]
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A fascinating Fe-promoted protocol for the synthesis of N-arylsulfonamides has been developed. Starting from commercially available nitroarenes and sulfonyl chlorides, moderate to excellent yields of the corresponding N-arylsulfonamides can be obtained. In particular, Fe dust serves as the sole reductant in the transformation and it can be easily performed on a large scale.
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