Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 27, Pages 5021-5026Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob01182f
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Funding
- National Natural Science Foundation of China [21572160]
- Program for Innovative Research Team in University of Tianjin [TD13-5074]
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A facile and practical [Cp*RhCl2](2)-catalyzed three-component reaction between indolyl aldehydes, amines and alkynes involving C-H activation and cyclization has been developed. A series of beta-carbolinium salts and gamma-carbolinium salts are successfully afforded in good to quantitative yields under mild conditions. This efficient and convergent strategy provides a good choice for constructing the libraries of beta-carbolinium salts and gamma-carbolinium
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