Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 17, Pages 3203-3212Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob00206a
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Funding
- Project of Youth Backbone Teachers of Henan University of Technology [2016003]
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A facile TBHP-mediated direct oxidative coupling of quinoxalin-2(1H)-ones with arylaldehydes has been developed under metal-free conditions. This method provided a convenient and efficient approach to various 3-acylated quinoxalin-2(1H)-ones from readily available starting materials with excellent regioselectivity. This reaction proceeded efficiently under mild conditions over a broad range of substrates and with functional group tolerance.
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