4.7 Review

Movement disorders in cerebrovascular disease

Journal

LANCET NEUROLOGY
Volume 12, Issue 6, Pages 597-608

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/S1474-4422(13)70057-7

Keywords

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Funding

  1. Allergan
  2. Allon Therapeutics
  3. Biotie
  4. Ceregene
  5. Chelsea Therapeutics
  6. Diana Hells Henry Medical Research Foundation
  7. EMD Serono
  8. Huntington's Disease Society of America
  9. Huntington Study Group
  10. Impax Pharmaceuticals
  11. Ipsen
  12. Lundbeck
  13. Medtronic
  14. Merz Pharmaceuticals
  15. Michael J Fox Foundation for Parkinson Research
  16. National Institutes of Health
  17. National Parkinson Foundation
  18. Neurogen
  19. St Jude Medical
  20. Teva Pharmaceutical Industries
  21. University of Rochester
  22. Parkinson Study Group

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Movement disorders can occur as primary (idiopathic) or genetic disease, as a manifestation of an underlying neurodegenerative disorder, or secondary to a wide range of neurological or systemic diseases. Cerebrovascular diseases represent up to 22% of secondary movement disorders, and involuntary movements develop after 1-4% of strokes. Post-stroke movement disorders can manifest in parkinsonism or a wide range of hyperkinetic movement disorders including chorea, ballism, athetosis, dystonia, tremor, myoclonus, stereotypies, and akathisia. Some of these disorders occur immediately after acute stroke, whereas others can develop later, and yet others represent delayed-onset progressive movement disorders. These movement disorders have been encountered in patients with ischaemic and haemorrhagic strokes, subarachnoid haemorrhage, cerebrovascular malformations, and dural arteriovenous fistula affecting the basal ganglia, their connections, or both.

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