Journal
3RD INTERNATIONAL CONFERENCE ON TISSUE ENGINEERING (ICTE2013)
Volume 59, Issue -, Pages 193-200Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.proeng.2013.05.110
Keywords
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Funding
- FRQS
- CIHR
- CUA Scolarship Fund
- Kidney foundation of Canada and Astellas Research Competition.
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Current urethral reconstruction procedures present many related complications. Moreover, the availability of urologic tissue is limited. Free of exogenous biomaterials, synthetic polymers or acellular matrices, a new tissue engineering technology has been optimized. This technique is known as self-assembly. The fibroblasts produce and assemble their own extracellular matrix to form a tissue very similar to native one. Goals are: to reconstruct a human urethral substitute containing a mature urothelium and a functional vascular network. The same substitute will also be produced using rabbit cells to allow autologous in vivo grafting. (C) 2013 The Authors. Published by Elsevier Ltd.
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