Journal
AMERICAN JOURNAL OF MEDICINE
Volume 128, Issue 9, Pages 943-949Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjmed.2015.02.018
Keywords
Allergy; Complications; Contrast; Extravasation; Fibrosis; Gadolinium; Induced; Intravenous; Metformin; Nephrogenic; Nephropathy; Systemic
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Intravenous contrast is commonly used in noninvasive imaging procedures such as magnetic resonance imaging and computed tomography and can evaluate blood vessels and better characterize soft-tissue lesions. Although the incidence of adverse events after administration of contrast is low, it is important that clinicians and radiologists minimize risks and respond quickly and effectively when reactions occur. We will discuss a range of adverse events to iodinated and gadolinium-based contrast agents, including allergic-like reactions, nephrotoxicity, extravasation, and nephrogenic systemic fibrosis. We will review risk stratification for patients, as well as premedication and treatment of adverse events. (C) 2015 Elsevier Inc. All rights reserved.
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