Journal
NEUROEPIDEMIOLOGY
Volume 50, Issue 3-4, Pages 174-182Publisher
KARGER
DOI: 10.1159/000487948
Keywords
Epidemiology; Stroke incidence; Sweden
Funding
- Swedish Heart and Lung Foundation
- Region Skane
- Skane University Hospital
- Freemasons Lodge of Instruction EOS, Lund
- Lund University
- Foundation of Fars and Frosta - one of Sparbanken Skane's ownership Foundations
- Swedish Stroke Association
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Background: Up-to-date epidemiological stroke studies are important for healthcare planning and evaluating prevention strategies. This population-based study investigates temporal trends in stroke incidence and case-fatality in southern Sweden. Methods: First-ever stroke cases in the local catchment area of %Me University Hospital in Lund, Sweden, between March, 2015 and February, 2016, were included from several sources, including 2 prospective hospital-based registers, retrospective screening of primary care visits, and autopsy registers. Stroke incidence and 28-day case-fatality rates were compared with data from this area obtained through similar methodology between March, 2001 and February, 2002. Results: Altogether, 456 and 413 first-ever stroke patients were identified during the earlier and later time periods respectively. The age- and sex-standardized stroke incidence rates decreased from 246 (95% CI 224-270) to 165 (95% CI 149-182) per 100,000 people. However, incidence remained unaltered among those <65 years. Early case-fatality decreased from 14 to 11% (p = 0.165). Conclusion: First-ever stroke incidence in southern Sweden has decreased to 33% since the beginning of this millennium. Incidence rates have decreased among the elderly but remain unchanged among younger age groups. Our findings warrant further studies on trends in risk factor profiles and effects of prevention strategies, and heightened focus on stroke in the young. (C) 2018 S. Karger AG, Basel
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