Preferential consolidation of emotionally salient information during a nap is preserved in middle age

Sleep preferentially preserves aspects of memory that are most salient and valuable to remember at the expense of memory for less relevant details. Daytime naps and nocturnal sleep enhance this emotional memory trade-off effect, with memory for emotional components correlated with slow-wave sleep during the day and rapid eye movement sleep overnight. However, these studies have primarily sampled from young adult populations. Sleep and memory are altered by middle age, and the aim of the present study was to examine how age affects sleep-based mechanisms of emotional memory prioritization, using a daytime nap protocol to compare young to middle-aged adults. In both age groups, a nap soon after encoding scenes that contained a negative or neutral object on a neutral background led to superior retention of emotional object memory at the expense of memory for the related backgrounds. Sleep spindle activity during slow-wave sleep was related to memory for this emotionally salient information across the age range. (C) 2018 Elsevier Inc. All rights reserved.