Journal
NATURE REVIEWS MICROBIOLOGY
Volume 16, Issue 6, Pages 383-390Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41579-018-0004-5
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Funding
- National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health [AR071731]
- National Science Foundation [1332344]
- US Department of Energy, Office of Science, Office of Biological & Environmental Research [DE-SC0012586, DE-SC0012658, DE-SC0018344]
- U.S. Department of Energy (DOE) [DE-SC0012586, DE-SC0012658] Funding Source: U.S. Department of Energy (DOE)
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Microorganisms engage in complex interactions with other organisms and their environment. Recent studies have shown that these interactions are not limited to the exchange of electron donors. Most microorganisms are auxotrophs, thus relying on external nutrients for growth, including the exchange of amino acids and vitamins. Currently, we lack a deeper understanding of auxotrophies in microorganisms and how nutrient requirements differ between different strains and different environments. In this Opinion article, we describe how the study of auxotrophies and nutrient requirements among members of complex communities will enable new insights into community composition and assembly. Understanding this complex network over space and time is crucial for developing strategies to interrogate and shape microbial communities.
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