4.7 Review

The new genetics of intelligence

Journal

NATURE REVIEWS GENETICS
Volume 19, Issue 3, Pages 148-159

Publisher

NATURE PORTFOLIO
DOI: 10.1038/nrg.2017.104

Keywords

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Funding

  1. UK Medical Research Council [MR/M021475/1]
  2. US National Institutes of Health [AG046938]
  3. European Research Council (ERC) under the European Union's Seventh Framework Programme [602768]
  4. ERC [295366]
  5. Medical Research Council Professorship award [G19/2]
  6. Jacobs Foundation Research Fellowship award
  7. MRC [G19/2, G0901245, MR/M021475/1] Funding Source: UKRI
  8. European Research Council (ERC) [295366] Funding Source: European Research Council (ERC)

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Intelligence - the ability to learn, reason and solve problems - is at the forefront of behavioural genetic research. Intelligence is highly heritable and predicts important educational, occupational and health outcomes better than any other trait. Recent genome-wide association studies have successfully identified inherited genome sequence differences that account for 20% of the 50% heritability of intelligence. These findings open new avenues for research into the causes and consequences of intelligence using genome-wide polygenic scores that aggregate the effects of thousands of genetic variants.

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