Related references
Note: Only part of the references are listed.TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ
Ismini E. Papageorgiou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology
Elizabeth E. Spangenberg et al.
BRAIN (2016)
The amyloid cascade hypothesis: are we poised for success or failure?
Eric Karran et al.
JOURNAL OF NEUROCHEMISTRY (2016)
3D culture models of Alzheimer's disease: a road map to a cure-in-a-dish
Se Hoon Choi et al.
MOLECULAR NEURODEGENERATION (2016)
Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
Dominik Paquet et al.
NATURE (2016)
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction
Zhen-Ning Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Soyon Hong et al.
SCIENCE (2016)
Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1
Alisa Tubsuwan et al.
STEM CELL RESEARCH (2016)
Alzheimer's in 3D culture: Challenges and perspectives
Carla D'Avanzo et al.
BIOESSAYS (2015)
A 3D human neural cell culture system for modeling Alzheimer's disease
Young Hye Kim et al.
NATURE PROTOCOLS (2015)
Deep two-photon brain imaging with a red-shifted fluorometric Ca2+ indicator
Carsten Tischbirek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer's disease pathology
Kuti Baruch et al.
NATURE COMMUNICATIONS (2015)
APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex Neurons
Steven Moore et al.
CELL REPORTS (2015)
Presence and Release of ATP from the Retina in an Alzheimer's Disease Model
Maria J. Perez de Lara et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
A critical analysis of the 'amyloid cascade hypothesis'
Richard A. Armstrong
FOLIA NEUROPATHOLOGICA (2014)
The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons
Christina R. Muratore et al.
HUMAN MOLECULAR GENETICS (2014)
A three-dimensional human neural cell culture model of Alzheimer's disease
Se Hoon Choi et al.
NATURE (2014)
Identification of a unique TGF-β dependent molecular and functional signature in microglia
Oleg Butovsky et al.
NATURE NEUROSCIENCE (2014)
Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors
Andrew A. Sproul et al.
PLOS ONE (2014)
Modeling Alzheimer's Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
Takayuki Kondo et al.
CELL STEM CELL (2013)
IFN-γ Production by Amyloid β-Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease
Tara C. Browne et al.
JOURNAL OF IMMUNOLOGY (2013)
Suppression of Inflammation with Conditional Deletion of the Prostaglandin E2 EP2 Receptor in Macrophages and Brain Microglia
Jenny U. Johansson et al.
JOURNAL OF NEUROSCIENCE (2013)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
NATURE (2013)
Blockage of CR1 prevents activation of rodent microglia
Helen Crehan et al.
NEUROBIOLOGY OF DISEASE (2013)
Alzheimer's Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
Ana Griciuc et al.
NEURON (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Presenilin-1 L166P Mutant Human Pluripotent Stem Cell Derived Neurons Exhibit Partial Loss of γ-Secretase Activity in Endogenous Amyloid-β Generation
Philipp Koch et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Microglial migration mediated by ATP-induced ATP release from lysosomes
Ying Dou et al.
CELL RESEARCH (2012)
Three-dimensional extracellular matrix-mediated neural stem cell differentiation in a microfluidic device
Sewoon Han et al.
LAB ON A CHIP (2012)
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
Mason A. Israel et al.
NATURE (2012)
Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research
Takuya Yagi et al.
PLOS ONE (2012)
Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture
C. J. Garwood et al.
CELL DEATH & DISEASE (2011)
Differential expression of interferon-γ receptor on human glial cells in vivo and in vitro
Sadayuki Hashioka et al.
JOURNAL OF NEUROIMMUNOLOGY (2010)
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
Joseph El Khoury et al.
NATURE MEDICINE (2007)
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
Sharon E. Haynes et al.
NATURE NEUROSCIENCE (2006)
Differential effects of oligomeric and fibrillar amyloid-β1-42 on astrocyte-mediated inflammation
JA White et al.
NEUROBIOLOGY OF DISEASE (2005)
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
RE Tanzi et al.
CELL (2005)
CD36 mediates the innate host response to β-amyloid
JB El Khoury et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Amyloid-β-induced chemokine production in primary human macrophages and astrocytes
HA Smits et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
Isolation and characterization of apolipoproteins from murine microglia - Identification of a low density lipoprotein-like apolipoprotein J-rich but E-poor spherical particle
Q Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)