4.8 Article

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

Related references

Note: Only part of the references are listed.
Review Cell Biology

Ubiquitin modifications

Kirby N. Swatek et al.

CELL RESEARCH (2016)

Review Cell Biology

The increasing complexity of the ubiquitin code

Richard Yau et al.

NATURE CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

Lenalidomide induces ubiquitination and degradation of CK1a in del(5q) MDS

Jan Kroenke et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Luke A. Gilbert et al.

Review Biochemistry & Molecular Biology

Cleaning up in the endoplasmic reticulum: ubiquitin in charge

John C. Christianson et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)

Article Multidisciplinary Sciences

Pharmacogenomic Approach to Identify Drug Sensitivity in Small-Cell Lung Cancer

Gary Wildey et al.

PLOS ONE (2014)

Article Multidisciplinary Sciences

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

Tim Wang et al.

SCIENCE (2014)

Review Biochemistry & Molecular Biology

The Ubiquitin Code

David Komander et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)

Editorial Material Cell Biology

Ubiquitin and SUMO in DNA repair at a glance

Helle D. Ulrich

JOURNAL OF CELL SCIENCE (2012)

Article Chemistry, Medicinal

Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)

Matthew O. Duffey et al.

JOURNAL OF MEDICINAL CHEMISTRY (2012)

Article Biochemical Research Methods

Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor

Dana Ungermannova et al.

JOURNAL OF BIOMOLECULAR SCREENING (2012)

Article Biochemistry & Molecular Biology

Mechanistic Studies of Substrate-assisted Inhibition of Ubiquitin-activating Enzyme by Adenosine Sulfamate Analogues

Jesse J. Chen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Biotechnology & Applied Microbiology

Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets

Lynn Bedford et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Review Cell Biology

The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 2: transcriptional regulation

Panagiotis J. Vlachostergios et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)

Article Multidisciplinary Sciences

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy et al.

NATURE (2009)

Article Genetics & Heredity

E1 Ubiquitin-Activating Enzyme UBA-1 Plays Multiple Roles throughout C. elegans Development

Madhura Kulkarni et al.

PLOS GENETICS (2008)

Article Genetics & Heredity

E1 Ubiquitin-Activating Enzyme UBA-1 Plays Multiple Roles throughout C-elegans Development

Madhura Kulkarni et al.

PLOS GENETICS (2008)

Article Multidisciplinary Sciences

Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging

Jianping Jin et al.

NATURE (2007)

Article Multidisciplinary Sciences

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

Mark G. Manfredi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemical Research Methods

The integration of macromolecular diffraction data

AGW Leslie

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)

Article Biochemical Research Methods

Scaling and assessment of data quality

P Evans

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

The ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle

A Hershko

CELL DEATH AND DIFFERENTIATION (2005)

Review Biochemistry & Molecular Biology

The comet assay for DNA damage and repair - Principles, applications, and limitations

AR Collins

MOLECULAR BIOTECHNOLOGY (2004)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Biochemical Research Methods

A graphical user interface to the CCP4 program suite

E Potterton et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2003)

Article Medicine, General & Internal

A phase 2 study of bortezomib in relapsed, refractory myeloma

PG Richardson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)