Related references
Note: Only part of the references are listed.Cancer metabolism: a therapeutic perspective
Ubaldo E. Martinez-Outschoorn et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
mTORC1 Activation Blocks BrafV600E-Induced Growth Arrest but Is Insufficient for Melanoma Formation
William Damsky et al.
CANCER CELL (2015)
Causes of genome instability: the effect of low dose chemical exposures in modern society
Sabine A. S. Langie et al.
CARCINOGENESIS (2015)
Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma
Antonio Calles et al.
CLINICAL CANCER RESEARCH (2015)
LKB1 preserves genome integrity by stimulating BRCA1 expression
Romi Gupta et al.
NUCLEIC ACIDS RESEARCH (2015)
ROS Function in Redox Signaling and Oxidative Stress
Michael Schieber et al.
CURRENT BIOLOGY (2014)
Making new contacts: the mTOR network in metabolism and signalling crosstalk
Mitsugu Shimobayashi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Possible involvement of LKB1-AMPK signaling in non-homologous end joining
A. Ui et al.
ONCOGENE (2014)
A Mouse Model Uncovers LKB1 as an UVB-Induced DNA Damage Sensor Mediating CDKN1A (p21WAF1/CIP1) Degradation
Rosaura Esteve-Puig et al.
PLOS GENETICS (2014)
The fine line between lifespan extension and shortening in response to caloric restriction
Kirk Szafranski et al.
NUCLEUS (2014)
Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks
Changxian Shen et al.
CANCER RESEARCH (2013)
RNF168 forms a functional complex with RAD6 during the DNA damage response
Chao Liu et al.
JOURNAL OF CELL SCIENCE (2013)
mTOR is a key modulator of ageing and age-related disease
Simon C. Johnson et al.
NATURE (2013)
Sinl phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis
Pengda Liu et al.
NATURE CELL BIOLOGY (2013)
Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1
Durga N. Tripathi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
Francesca Mattiroli et al.
CELL (2012)
TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes
Thorkell Gudjonsson et al.
CELL (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Cancer Cell Metabolism: One Hallmark, Many Faces
Jason R. Cantor et al.
CANCER DISCOVERY (2012)
Double-Strand Break End Resection and Repair Pathway Choice
Lorraine S. Symington et al.
ANNUAL REVIEW OF GENETICS, VOL 45 (2011)
Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors
Thomas De Raedt et al.
CANCER CELL (2011)
The role of LKB1 and AMPK in cellular responses to stress and damage
Angela Alexander et al.
FEBS LETTERS (2011)
The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling
W. van Veelen et al.
ONCOGENE (2011)
Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome
Toshiyuki Bohgaki et al.
PLOS GENETICS (2011)
The ubiquitous role of ubiquitin in the DNA damage response
Abdallah Al-Hakim et al.
DNA REPAIR (2010)
Quantitative Nuclear Proteomics Identifies mTOR Regulation of DNA Damage Response
Sricharan Bandhakavi et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Cellular Metabolic Stress: Considering How Cells Respond to Nutrient Excess
Kathryn E. Wellen et al.
MOLECULAR CELL (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
Angela Alexander et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
Carsten Doil et al.
CELL (2009)
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
Grant S. Stewart et al.
CELL (2009)
Cdh1 Regulates Cell Cycle through Modulating the Claspin/Chk1 and the Rb/E2F1 Pathways
Daming Gao et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APC-Cdh1-mediated Skp2 destruction
Daming Gao et al.
NATURE CELL BIOLOGY (2009)
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
David B. Shackelford et al.
NATURE REVIEWS CANCER (2009)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
Nadine K. Kolas et al.
SCIENCE (2007)
Caloric restriction and genomic stability
Ahmad R. Heydari et al.
NUCLEIC ACIDS RESEARCH (2007)
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
Michael S. Y. Huen et al.
CELL (2007)
TOR signaling is a determinant of cell survival in response to DNA damage
Changxian Shen et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
LKB1 modulates lung cancer differentiation and metastasis
Hongbin Ji et al.
NATURE (2007)
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
Ken Inoki et al.
CELL (2006)
The comet assay: a method to measure DNA damage in individual cells
Peggy L. Olive et al.
NATURE PROTOCOLS (2006)
Clonogenic assay of cells in vitro
Nicolaas A. P. Franken et al.
NATURE PROTOCOLS (2006)
Transformation of human and murine fibroblasts without viral oncoproteins
JS Boehm et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Expression and purification of recombinant human histones
Y Tanaka et al.
METHODS (2004)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)
DNA double-strand breaks: signaling, repair and the cancer connection
KK Khanna et al.
NATURE GENETICS (2001)