4.4 Article

A phytochemical study of the Cuphea glutinosa from Southern Brazil: Na+,K+-ATPase activity inhibition and antioxidant properties

Journal

NATURAL PRODUCT RESEARCH
Volume 33, Issue 23, Pages 3426-3431

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1477143

Keywords

Cuphea glutinosa; phytochemistry; scavenger properties; Na+; K+-ATPase

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This study investigated the antioxidant activity of Cuphea glutinosa (CG) and its effect on Na+, K+-ATPase from cardiac muscle. The ethanolic extract showed higher antioxidant capacity compared to aqueous and ethyl acetate fraction. Ethyl acetate fraction showed ?-sitosterol-3-O-?-glucoside, kaempferol, quercetin, isoquercetin, gallic acid methyl ester, and gallic acid. The ethanolic extract also reduced the Na+,K+-ATPase activity. CG presented a promising antioxidant activity and inhibitory effect on the Na+, K+-ATPase activity, supporting biochemical evidences the popular use of this plant in the treatment of heart failure.

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