Journal
NATURAL PRODUCT RESEARCH
Volume 33, Issue 22, Pages 3283-3286Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1468332
Keywords
Auricularia auricula-judae (Bull; ); mushroom; antioxidant; skin; collagen; HAS-3; HaCaT cells
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Funding
- Jeonju AgroBio-Materials Institute, Korea
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In this study, Auricularia auricula-judae (Bull.) extract (AAE) had potent antioxidant activity in vitro and promoted the biosynthesis of procollagen, a precursor of collagen in HaCaT cells. In addition, the expression of HAS-3 (hyaluronic acid synthase), which is a moisturizing factor, was increased in HaCaT cells in response to AAE. Therefore, this work suggests that AAE has the potential to exhibit antioxidant activity and promote procollagen biosynthesis in HaCaT cells.
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