Journal
NATURAL PRODUCT REPORTS
Volume 35, Issue 6, Pages 514-531Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8np00011e
Keywords
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Funding
- U.S. National Institutes of Health [ICBG U19-TW007401]
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This article reviews recent reports on the structural revision of natural products. Through a critical assessment of the original and revised published structures, the article addresses why each structure was targeted for revision, discusses the techniques and key discrepancies that led to the proposal of the revised structure, and offers measures that may have been taken during the original structure determination to prevent error. With the revised structures in hand, weaknesses of original proposals are assessed, providing a better understanding on the logic behind structure determination.
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