4.8 Article

A bumpy gold nanostructure exhibiting DNA-engineered stimuli-responsive SERS signals

Journal

NANOSCALE
Volume 10, Issue 20, Pages 9455-9459

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8nr00986d

Keywords

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Funding

  1. National Science Foundation China [21573051, 51761145044]
  2. Science Fund for Creative Research Groups of the National Natural Science Foundation of China [21721002]
  3. National Basic Research Programs of China [2016YFA0201601]
  4. Beijing Municipal Science & Technology Commission [Z161100000116036]
  5. Key Research Program of Frontier Sciences, CAS [QYZDB-SSW-SLH029]
  6. CAS Interdisciplinary Innovation Team
  7. K. C. Wong Education Foundation
  8. Youth Innovation Promotion Association CAS
  9. CAS Key Laboratory of Nanosystem and Hierarchical Fabrication

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We present a SERS-active gold nanostructure with built-in electromagnetic hotspots formed by densely packed gold nanoparticles on a gold nanorod. Cy3 labeled stimuli-responsive DNA motifs were introduced to the SERS-active nanostructure. The SERS signals can be switched ON and OFF reversibly in response to external stimuli (pH, metal ions or organic molecules).

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