4.2 Article

SYNTHESIS OF ISOCOUMARINS: RHENIUM COMPLEX-CATALYZED CYCLIZATION OF 2-ETHYNYLBENZOIC ACIDS

Journal

HETEROCYCLES
Volume 91, Issue 11, Pages 2172-2179

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-15-13311

Keywords

Rhenium Complex; Isocoumarin; 6-endo-Intramolecular Cyclization; 2-Ethynylbenzoic Acid

Funding

  1. Kansai University Research Grants

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When 2-ethynylbenzoic acids were treated with a catalytic amount of a rhenium complex, such as ReCl(CO())5, 6-endo cyclization of 2-ethynylbenzoic acids proceeded with a high selectivity to give the corresponding isocoumarins in moderate to good yields.

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