Journal
HETEROCYCLES
Volume 91, Issue 10, Pages 1863-1903Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/REV-15-824
Keywords
3-Substituted Chromone; Nucleophilic Reaction; Nitrogen and Carbon Nucleophile; RORC; Heterocyclizatiz Raction
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This review covers the ring opening ring closure (RORC) reactions of 3-substituted chromones with a variety of nitrogen and carbon nucleophiles. The nucleophilic reagent usually attack 3-substituted chromones at the C-2 position with gamma-pyrone ring opening followed by further transformation during the course of the reaction producing a variety of products depending on the substrate at position 3, the nature of nucleophile and the reaction conditions.
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