Journal
HETEROCYCLES
Volume 91, Issue 10, Pages 1964-1971Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-15-13277
Keywords
Nano-Copper Catalysis; Cycloaddition Reaction; N-Alkylation Reaction; Tandem Reaction; Multicomponent Reaction
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Funding
- Natural Science Foundation of China [20702042, 21262028]
- Program for Changjiang Scholars and Innovative Research Teams in Universities of the Ministry of Education of China [IRT1177]
- Natural Science Foundation of Gansu Province [1208RJZA140]
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Nano-copper catalyzed one-pot three-component method is realized from aminophenylacetylenes, sodium azide and alkyl halides via tandem 3+2 dipolar cycloaddition reaction and N-alkylation reaction. This synthetic process gave the product of 1-alkyl-4-(N-alkylaminophenyl)-1H-1,2,3-triazoles in good yields.
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